| SPRINGFIELD C.C., INC. | — | 73389 | 1977-05-06 | Dissolved | SPRINGFIELD |
| SPRINGFIELD COLLEGE | Educational services | 51827 | 1993-12-30 | Suspended | SPRINGFIELD |
| SPRINGFIELD COMMUNITY BAND, INC. | Arts and entertainment | 326385 | 2017-02-01 | Active | Springfield |
| SPRINGFIELD COMMUNITY PLAYERS, INC. | Arts and entertainment | 44700 | 1972-08-29 | Active | SPRINGFIELD |
| SPRINGFIELD CONVENIENCE, INC. | — | 292278 | 2014-06-09 | Dissolved | SPRINGFIELD |
| SPRINGFIELD DOWNTOWN REDEVELOPMENT, INC. | — | 112734 | 1994-12-27 | Revoked | SPRINGFIELD |
| SPRINGFIELD ELECTROPLATING COMPANY, INC. | — | 48051 | 1946-03-07 | Revoked | SPRINGFIELD |
| SPRINGFIELD ELKS CLUB, INC. | — | 44701 | 1929-11-21 | Active | SPRINGFIELD |
| SPRINGFIELD EVENTS, INC. | — | 76056 | 2004-12-14 | Dissolved | SPRINGFIELD |
| SPRINGFIELD FAMILY CENTER, INC. | Health care and social assistance | 44702 | 1973-12-18 | Active | Springfield |
| SPRINGFIELD FARMERS MARKET INC | — | 316897 | 2016-03-25 | Revoked | Springfield |
| SPRINGFIELD FOODSERVICE, LLC | — | 20239 | 2007-07-25 | Inactive | SPRINGFIELD |
| SPRINGFIELD GARDEN CLUB, INC. | — | 283624 | 2013-10-30 | Active | Springfield |
| SPRINGFIELD GRANGE NO. 114, INC. | — | 44704 | 1963-03-06 | Revoked | SPRINGFIELD |
| SPRINGFIELD GROUP, INC. THE | — | 94276 | 1984-05-16 | Revoked | SPRINGFIELD |
| SPRINGFIELD HOCKEY ASSOCIATION, INCORPORATED | — | 44705 | 1978-10-06 | Revoked | SPRINGFIELD |
| SPRINGFIELD HOSPITAL AUXILIARY, INC. | — | 44707 | 1958-05-26 | Revoked | SPRINGFIELD |
| SPRINGFIELD HOSPITAL INC. | Health care and social assistance | 44706 | 1913-08-13 | Active | SPRINGFIELD |
| SPRINGFIELD HOUSING UNLIMITED | Public administration | 48635 | 1989-01-31 | Active | SPRINGFIELD |
| SPRINGFIELD HUMANE SOCIETY, INC. | Other services | 44708 | 1956-10-16 | Active | SPRINGFIELD |
| SPRINGFIELD IMAGE, LLC | — | 6688 | 2002-03-01 | Revoked | SPRINGFIELD |
| SPRINGFIELD INDUSTRIAL GROUP, LLC | — | 21732 | 2006-01-23 | Revoked | SPRINGFIELD |
| SPRINGFIELD INVESTORS, INC. | — | 109060 | 1992-09-14 | Dissolved | SPRINGFIELD |
| SPRINGFIELD LABEL & TAPE CO., INC. | — | 68563 | 1997-08-13 | Active | SPRINGFIELD |
| SPRINGFIELD LEARNING GARDEN, INC. | — | 49547 | 1990-07-30 | Active | Springfield |
| SPRINGFIELD LODGE NO. 679, LOYAL ORDER OF MOOSE, INC. | Other services | 44709 | 1948-02-02 | Active | SPRINGFIELD |
| SPRINGFIELD MASONIC ASSOCIATION, INC. | — | 46719 | 1936-03-23 | Dissolved | SPRINGFIELD |
| SPRINGFIELD MEDICAL CARE SYSTEMS, INC. | Health care and social assistance | 44711 | 1982-05-12 | Active | Springfield |
| SPRINGFIELD METALLURGICAL SERVICES, INC. | — | 122971 | 2002-05-31 | Dissolved | SPRINGFIELD |
| SPRINGFIELD NET METERING, LLC | — | 37360 | 2012-03-26 | Active | SPRINGFIELD |
| SPRINGFIELD ON THE MOVE | — | 53659 | 1996-06-28 | Active | SPRINGFIELD |
| SPRINGFIELD ORTHODONTICS, PLLC | — | 288217 | 2014-01-27 | Suspended | Springfield |
| SPRINGFIELD PAIN CLINIC, INC | — | 413738 | 2022-08-08 | Dissolved | Springfield |
| SPRINGFIELD PARTNERS, INC. | — | 96958 | 1985-11-27 | Revoked | SPRINGFIELD |
| SPRINGFIELD PAVING CORPORATION | — | 102310 | 1988-09-01 | Revoked | SPRINGFIELD |
| SPRINGFIELD PBV LEASING, INC. | Real estate and leasing | 320226 | 2016-06-26 | Revoked | Springfield |
| SPRINGFIELD PEDIATRIC ASSOCIATES, P.C. | — | 109572 | 1993-01-13 | Dissolved | SPRINGFIELD |
| SPRINGFIELD PHARMACY, INC. | — | 121634 | 2001-04-27 | Active | SPRINGFIELD |
| SPRINGFIELD PHYSICIAN HOSPITAL ORGANIZATION, L.L.C. | — | 5304 | 2000-06-08 | Revoked | SPRINGFIELD |
| SPRINGFIELD PREVENTION COALITION, INC | — | 76310 | 2005-03-14 | Dissolved | Springfield |
| SPRINGFIELD PRIDE CORP | Other services | 317183 | 2016-04-01 | Dissolved | springfield |
| SPRINGFIELD PROJECT ACTION, INC. | Other services | 318747 | 2016-05-12 | Dissolved | Springfield |
| SPRINGFIELD PROJECT GROUP, INC. | — | 100462 | 1987-10-05 | Revoked | SPRINGFIELD |
| SPRINGFIELD PROPERTY CORPORATION | — | 44712 | 1982-05-12 | Revoked | SPRINGFIELD |
| SPRINGFIELD RACQUET CLUB, INC. | — | 82923 | 1981-01-26 | Revoked | SPRINGFIELD |
| SPRINGFIELD REALTY CORPORATION | Real estate and leasing | 56612 | 1961-11-28 | Active | SPRINGFIELD |
| SPRINGFIELD REDEMPTION CENTER, INC. | — | 98860 | 1986-12-22 | Revoked | SPRINGFIELD |
| SPRINGFIELD REGIONAL CHAMBER OF COMMERCE, INC. | — | 44696 | 1958-03-06 | Active | SPRINGFIELD |
| SPRINGFIELD REGIONAL DEVELOPMENT CORPORATION | — | 50584 | 1992-04-17 | Active | SPRINGFIELD |
| SPRINGFIELD REPORTER, INCORPORATED | — | 116450 | 1997-04-09 | Active | SPRINGFIELD |